Journal:

Article Title: Quality Control Guidelines for MIC Susceptibility Testing of Omiganan Pentahydrochloride (MBI 226), a Novel Antimicrobial Peptide

doi: 10.1128/JCM.42.3.1386-1387.2004

Figure Lengend Snippet: Proposed MIC QC ranges for omiganan listed by medium type a

Article Snippet: The proposed omiganan MIC QC ranges also were 1 log 2 dilution higher for CA-MHB when E. coli ATCC 25922 was used (Table ). table ft1 table-wrap mode="anchored" t5 caption a7 QC organism Omiganan MIC (μg/ml) QC range (% in range) for: CA-MHB MHB RPMI 1640 E. faecalis ATCC 29212 32-128 (100.0) 32-128 (100.0) S. aureus ATCC 29213 8-64 (99.5) 4-32 (100.0) S. pneumoniae ATCC 49619 b 32-128 (100.0) 16-64 (100.0) E. coli ATCC 25922 16-64 (99.0) 8-32 (100.0) P. aeruginosa ATCC 27853 64-256 (100.0) 8-64 (100.0) C. parapsilosis ATCC 22019 32-128 (99.0) C. krusei ATCC 6258 16-64 (100.0) Open in a separate window a RPMI 1640 was used for all tests of yeast. b Lysed horse blood (2 to 5%) was added to CA-MHB for testing this QC strain.

Techniques:

Journal: Archives of ophthalmology

Article Title: Evaluation of Visual Acuity Measurements after Autorefraction versus Manual Refraction in Eyes with and without Diabetic Macular Edema

doi: 10.1001/archophthalmol.2011.377

Figure Lengend Snippet: Autorefractor used (N=964) - N (%)

Article Snippet: Of the Topcon models, the 8000 series autorefractors differed from other autorefractor models included in this study in that they utilize a rotary prism technology that theoretically enables measurements of a wider retinal area through a smaller diameter pupil. table ft1 table-wrap mode="anchored" t5 caption a7 Canon RK-2 2 (<1%) Canon RK-FI 8 (<1%) Grand Seiko WR-5100K 42 (4%) Humphrey 599 56 (6%) Marco Epic 2100 14 (1%) Marco Nidek ARK700A 44 (5%) Marco Nidek ARK730A 18 (2%) Marco Nidek ARK760A 204 (21%) Nidek AR 800 20 (2%) Nidek AR3000 90 (9%) Nidek ARK-900 12 (1%) Nikon NRK-8000 28 (3%) Nikon Retinomax 2 8 (<1%) Nikon Speedy 1 2 (<1%) Nikon Speedy K 6 (<1%) Topcon KR3000 38 (4%) Topcon KR7000S 2 (<1%) Topcon KR8000 142 (15%) Topcon KR8800 60 (6%) Topcon KR8900 132 (14%) Topcon RM 8000 14 (1%) Topcon RM A7000 22 (2%) Open in a separate window Autorefractor used (N=964) - N (%)

Techniques:

Journal: Expert Review of Pharmacoeconomics & Outcomes Research

Article Title: Economic evaluations of neuraminidase inhibitors to control influenza

doi: 10.1586/14737167.3.2.147

Figure Lengend Snippet: Neuraminidase inhibitors

Article Snippet: [ 18 , 35 ] Moreover ion-channel M2 inhibitors are rarely used in some developed countries, or even removed from the pharmacopoeia (e.g. rimantadine in France). table ft1 table-wrap mode="anchored" t5 caption a7 Name Zanamivir Oseltamivir Peramivir Drug name GG167 GS4104 BCX-1812 (formerly RWJ270201) Proprietary name Relenza Tamiflu - Manufacturers Biota & GlaxoSmithKline Gilead & Hoffman-La Roche BioCryst (partnership dissolved with Johnson & Johnson in 2001) First approval in USA 1999 1999 ND First approval in Japan 2000 2001 ND First approval in European Union 1999 2002 ND Indications in 2002: - treatment of influenza A and B in adults Yes Yes - - treatment of influenza A and B in children > 7 years > 1 year - - prevention of influenza A and B in adults and adolescents No Yes - Key features differentiating NA inhibitors: Route of administration Dry power self- administred via oral inhalation Oral capsule or suspension form Oral Recommended daily dosage 10 mg twice daily 75 mg twice daily (once daily if prevention) Once daily Adverse effects compared to a placebo in randomized controlled trials No increase (each adverse event <5%) Nausea and vomiting more frequent in adults and children (1% discontinued) No increase expected Limitation of usage Patients with underlying airway disease No No Post-treatment isolates with decreased susceptibility No (but the number of tests is limited) 1.3% after >13 years to 8.6% among 1–12 years - Price in USA 44.40 $ 55.13$ - Price in UK 24 pounds - - Price in France 22.4 euros 30 euros - Open in a separate window Neuraminidase inhibitors

Techniques: Suspension

Journal: Expert Review of Pharmacoeconomics & Outcomes Research

Article Title: Economic evaluations of neuraminidase inhibitors to control influenza

doi: 10.1586/14737167.3.2.147

Figure Lengend Snippet: Economic evaluations of systematic prescription of NA inhibitors (all costs are rounded to US$)

Article Snippet: [ 18 , 35 ] Moreover ion-channel M2 inhibitors are rarely used in some developed countries, or even removed from the pharmacopoeia (e.g. rimantadine in France). table ft1 table-wrap mode="anchored" t5 caption a7 Name Zanamivir Oseltamivir Peramivir Drug name GG167 GS4104 BCX-1812 (formerly RWJ270201) Proprietary name Relenza Tamiflu - Manufacturers Biota & GlaxoSmithKline Gilead & Hoffman-La Roche BioCryst (partnership dissolved with Johnson & Johnson in 2001) First approval in USA 1999 1999 ND First approval in Japan 2000 2001 ND First approval in European Union 1999 2002 ND Indications in 2002: - treatment of influenza A and B in adults Yes Yes - - treatment of influenza A and B in children > 7 years > 1 year - - prevention of influenza A and B in adults and adolescents No Yes - Key features differentiating NA inhibitors: Route of administration Dry power self- administred via oral inhalation Oral capsule or suspension form Oral Recommended daily dosage 10 mg twice daily 75 mg twice daily (once daily if prevention) Once daily Adverse effects compared to a placebo in randomized controlled trials No increase (each adverse event <5%) Nausea and vomiting more frequent in adults and children (1% discontinued) No increase expected Limitation of usage Patients with underlying airway disease No No Post-treatment isolates with decreased susceptibility No (but the number of tests is limited) 1.3% after >13 years to 8.6% among 1–12 years - Price in USA 44.40 $ 55.13$ - Price in UK 24 pounds - - Price in France 22.4 euros 30 euros - Open in a separate window Neuraminidase inhibitors

Techniques: Control

Journal: Ultramicroscopy

Article Title: RANKING TEM CAMERAS BY THEIR RESPONSE TO ELECTRON SHOT NOISE

doi: 10.1016/j.ultramic.2013.01.003

Figure Lengend Snippet: Use of azimuthally averaged Fourier amplitude spectra of empty images to rank the performance of different electronic cameras. Individual Lorentzian functions, which are of the form 11+(ss0)2, are fitted to each Fourier amplitude spectrum. Three parameters – an overall scale factor for each experimental amplitude spectrum, an additive constant, and s0, the spatial frequency at which the function is equal 0.5 – are varied to produce a least-squares best fit between the data and the analytical function. (A) The Fourier amplitude spectrum for the TVIPS TemCam F416 camera, obtained when using 120 keV electrons, is used to illustrate the fitting of a single Lorentzian function to the experimental amplitude spectrum. Corresponding figures for other cameras are shown in the Supplemental material. (B) Comparison of Lorentzian curves fitted to amplitude spectra for two types of scintillator-coupled camera and for a silicon-pixel camera. Solid line: TVIPS TemCam F416 camera, 120 keV electrons; dashed line: Gatan UltraScan 4000 camera, 200 keV electrons; dotted line, Gatan K2 camera, 300 keV electrons.

Article Snippet: For two of these cameras we were also able to make these measurements for two values of the incident electron energy. table ft1 table-wrap mode="anchored" t5 caption a7 TVIPS F416 4kx4k 15.6 μm pixel Gatan US4000 4kx4k 15.0 μm pixel FEI Eagle 2kx2k 30 μm pixel Gatan K2 4kx4k 5 μm pixel 80 keV - - 0.1 - 120 keV 1.1 1.2 - - 200 keV - 1.7 - - 300 keV - - 1.0 1.1 Open in a separate window Estimated variance of the detector response to single-electron events, derived from the excess noise (at low frequency) in the power spectra of empty images, depending upon the type of detector and the electron energy.

Techniques: Comparison

Journal: Ultramicroscopy

Article Title: RANKING TEM CAMERAS BY THEIR RESPONSE TO ELECTRON SHOT NOISE

doi: 10.1016/j.ultramic.2013.01.003

Figure Lengend Snippet: Values of the spatial frequency, expressed as a fraction of Nyquist frequency, at which Lorentzian functions – fitted to the Fourier amplitude spectra of “empty” images – fall to 0.5, depending upon the type of detector and the electron energy. The sum of a single Lorentzian function plus a constant y-axis offset was fitted to the Fourier amplitude spectra (see for an example). Please refer to Figure S1 for fitted amplitude spectra for all other examples listed in this table. Values given in parentheses are the reciprocal of the respective values of the spatial frequency, i.e. the distance in number of pixels at which the nearly exponential linespread function falls to e −1 . Recall that Nyquist frequency is 1/(2 pixel).

Article Snippet: For two of these cameras we were also able to make these measurements for two values of the incident electron energy. table ft1 table-wrap mode="anchored" t5 caption a7 TVIPS F416 4kx4k 15.6 μm pixel Gatan US4000 4kx4k 15.0 μm pixel FEI Eagle 2kx2k 30 μm pixel Gatan K2 4kx4k 5 μm pixel 80 keV - - 0.1 - 120 keV 1.1 1.2 - - 200 keV - 1.7 - - 300 keV - - 1.0 1.1 Open in a separate window Estimated variance of the detector response to single-electron events, derived from the excess noise (at low frequency) in the power spectra of empty images, depending upon the type of detector and the electron energy.

Techniques:

Journal: Ultramicroscopy

Article Title: RANKING TEM CAMERAS BY THEIR RESPONSE TO ELECTRON SHOT NOISE

doi: 10.1016/j.ultramic.2013.01.003

Figure Lengend Snippet: Examples of azimuthally averaged power spectra of empty images that have been normalized by N, the total number of electrons in a given image. Only three examples are shown here for simplicity. Corresponding figures for other cameras are shown in the Supplemental material. Red curve: TVIPS F416 camera, 120 keV electrons; green curve: Gatan US4000 camera, 200 keV electrons; blue curve: Gatan K2 camera, 300 keV electrons.

Article Snippet: For two of these cameras we were also able to make these measurements for two values of the incident electron energy. table ft1 table-wrap mode="anchored" t5 caption a7 TVIPS F416 4kx4k 15.6 μm pixel Gatan US4000 4kx4k 15.0 μm pixel FEI Eagle 2kx2k 30 μm pixel Gatan K2 4kx4k 5 μm pixel 80 keV - - 0.1 - 120 keV 1.1 1.2 - - 200 keV - 1.7 - - 300 keV - - 1.0 1.1 Open in a separate window Estimated variance of the detector response to single-electron events, derived from the excess noise (at low frequency) in the power spectra of empty images, depending upon the type of detector and the electron energy.

Techniques:

Journal: Ultramicroscopy

Article Title: RANKING TEM CAMERAS BY THEIR RESPONSE TO ELECTRON SHOT NOISE

doi: 10.1016/j.ultramic.2013.01.003

Figure Lengend Snippet: Estimated variance of the detector response to single-electron events, derived from the excess noise (at low frequency) in the power spectra of empty images, depending upon the type of detector and the electron energy.

Article Snippet: For two of these cameras we were also able to make these measurements for two values of the incident electron energy. table ft1 table-wrap mode="anchored" t5 caption a7 TVIPS F416 4kx4k 15.6 μm pixel Gatan US4000 4kx4k 15.0 μm pixel FEI Eagle 2kx2k 30 μm pixel Gatan K2 4kx4k 5 μm pixel 80 keV - - 0.1 - 120 keV 1.1 1.2 - - 200 keV - 1.7 - - 300 keV - - 1.0 1.1 Open in a separate window Estimated variance of the detector response to single-electron events, derived from the excess noise (at low frequency) in the power spectra of empty images, depending upon the type of detector and the electron energy.

Techniques: Derivative Assay